Rotterdam, The Netherlands
30 April - 4 May 2011


Programme

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Programme (pdf) (3.14mb)


30 April 2011
     
     
 12:00 20:00    Registration
     
 15:00 17:00    Satellite Symposium: Growth hormone: less and in excess
Sponsored by Sandoz
Willem Burger Auditorium
Chairs: G. Stalla & M. Pfeifer
15:00 Welcome
G. Stalla & M. Pfeifer
15:10 Metabolic consequences of growth hormone deficiences
P. Chanson
15:35 Different causes of pituitary insufficiency
G. Aimaretti
16:00 More than a decade of growth hormone substitution: what have we learnt?
S. Shalet
16:25 Growth hormone abuse
M. Bidlingmeier
16:50 Closing remarks
     
 17:30 18:05    Opening Ceremony: Welcome & Introduction
Main Auditorium
Chair: E. Nieschlag (Germany)
17:30 Introduction & Welcome to ECE 2011
E. Nieschlag (Germany)
17:45 Welcome to Rotterdam & ECE 2011
P. Trainer (UK) & W. de Herder (The Netherlands)
     
 18:05 18:45    Opening Ceremony: Geoffrey Harris Prize Lecture
Main Auditorium
Chair: B. Jarzab (Poland)
18:10 GH1 GHRELIN: a neuroendocrine and/or metabolic story?
E. Ghigo (Italy)
     
 18:45 19:30    Opening Ceremony: European Journal of Endocrinology Prize Lecture
Main Auditorium
Chair: C. Strasburger - Editor-in-Chief of EJE (Germany)
     
 19:30 21:00    ECE 2011 Welcome Reception
Exhibition Hall
     
 21:30    
     
1 May 2011
 06:30 20:00    Registration
     
 06:45 07:50    Handbook of Cushing's Disease Book Launch
Generously supported by Novartis
Willem Burger Auditorium
06:45 Breakfast reception
07:15 Welcome & Introduction
SWJ Lamberts
07:25 Different treatment options, which and when? What does the future hold?
R. Pivonello
07:40 Q&A and book distribution
     
 08:00 08:45    Plenary Lecture 1
Main Auditorium
Chair: P. Beck - Peccoz
08:00 PL1 Disorders of sex development (DSD)
T. Ogato (Japan)
     
 08:45 09:00    Presidential Address
Main Auditorium
     
 09:05 10:35    Symposium 1: Keep cool, lose weight: brown fat and energy metabolism
Willem Burger Auditorium
Chairs: J. Romijn (The Netherlands) & U. Pagotto (Italy)
09:05 S1.1 Brown adipocytes and energy homeostasis in mice
S. Herzig (Germany)
09:35 S1.2 Physiology of brown adipose tissue in humans
P. Nuutila (Finland)
10:05 S1.3 Brown adipose tissue and thermogenesis in lean and obese subjects
W. van Marken (The Netherlands)
     
 09:05 10:35    Symposium 2: Controversies in hyperaldosteronism
Main Auditorium
Chairs: M. Coculescu (Romania) & P. Stewart (UK)
09:05 S2.1 Controversies in hyperaldosteronism: whom and how to screen
P. Mulatero (Italy)
09:35 S2.2 Adrenal vein sampling
T. Zelinka (Czech Republic)
10:05 S3.3 Non surgical therapy of primary aldosteronism
M. Stowasser (Australia)
     
 09:05 10:35    Symposium 3: Molecular mechanisms in neuroendocrine tumours
Fortis Bank Hall
Chairs: L. Hofland (The Netherlands) & J. Castano (Spain)
09:05 S3.1 Somatostatin and dopamine signalling in neuroendocrine tumours
D. Ferone (Italy)
09:35 S3.2 A new truncated variant of somatostatin receptor subtype five, sst5TMD4, is present in pituitary tumours and breast cancer, and impairs the normal response to somatostatin
J. Castano (Spain)
10:05 S3.3 Lessons from MENX
N. Pellegata (Germany)
     
 09:05 10:35    Symposium 4: Subclinical hormone excess
Jurriaanse Auditorium
Chairs: W. Wiersinga (The Netherlands) & M. Terzolo (Italy)
09:05 S4.1 Subclinical adrenal hyperfunction
G. Kaltas (Greece)
09:35 S4.2 Normocalcemic primary hyperparathyroidism
F. Cetani (Italy)
10:05 S4.3 Subclinical hyperthyroidism
B. Biondi (Italy)
     
 10:35 11:00    Coffee Break & Exhibition
Exhibition Hall
     
 11:00 12:00    Debate 1: This house believes that far too few post-menopausal women receive oestrogen therapy
For: J. Studd (London); Against: J Foidart (Belgium)
Main Auditorium
Chair: P. Bouchard
France
     
 11:00 11:45    Meet the Expert 1
Willem Burger Auditorium
11:00 MTE1 Pros and cons of bariatric surgery
J. Salvador (Spain)
     
 11:00 11:45    Meet the Expert 2
Jurriaanse Auditorium
11:00 MTE2 Primary hyperaldosteronism
M. Stowasser (Australia)
     
 11:00 11:45    Meet the Expert 3
Fortis Bank Hall
11:00 MTE3 Difficult recurrences and metastasis of thyroid cancer
L. Leenhardt (France)
     
 11:00 11:45    Meet the Expert 4
Van Ruckevorsal Hall
11:00 MTE4 Mass spectrometry in the measurement of hormones
U. Pagotto (Italy)
     
 11:00 11:45    Meet the Expert 5
Van der Vorm Hall
11:00 MTE5 How to write a manuscript - Meet the Editor
C. Strasburger (Germany)
     
 12:00 12:40    Lunch & Exhibition
ESE President meets ESE Affiliated Society Presidents (invitation only)
Exhibition Hall
     
 12:40 14:10    Symposium 5: Novel therapies in type-1 diabetes
Willem Burger Auditorium
Chairs: J. Skrha (Czech Republic) & J. Christiansen (Denmark)
12:40 S5.1 Pancreas transplantation
T. Berney (Switzerland)
13:10 S5.2 Islet transplantation and regeneration
E. de Koning (NL)
13:40 S5.3 Stem cells as a treatment option in diabetes mellitus
J. Kerr-Conte (France)
     
 12:40 14:10    Symposium 6: Long term effects of bisphosphonates
Main Auditorium
Chairs: M. Bolanowski (Poland) & V. Rochira (Italy)
12:40 S6.1 The risk of fractures and osteonecrosis
B. Abrahamsen (Denmark)
13:10 S6.2 Long term management of osteoporosis
E. Eriksen (Norway)
13:40 S6.3 Bone turnover markers in the management of osteoporosis
M. Seibel (Australia)
     
 12:40 14:10    Symposium 7: Novel approaches to in vitro and in vivo imaging
Fortis Bank Hall
Chairs: TBC & W. Arlt (UK)
12:40 S7.1 How to visualize G-protein coupled receptor signaling by FRET
D. Calebiro (Germany)
13:10 S7.2 Multiphoton microscopy to visualize cell migration and invasion
K. Wolf (The Netherlands)
13:40 S7.3 Molecular and clinical imaging of adrenal steroidogenesis by iodometomidate
S. Hahner (Germany)
     
 12:40 14:10    Symposium 8: The biological clock and metabolism
Jurriaanse Auditorium
Chairs: S. La Fleur (The Netherlands) & TBC
12:40 S8.1 Clock genes in human adipose tissue
M. Garaulet (Spain)
13:10 S8.2 Circadian clock regulation of glucocorticoid synthesis
H. Oster (Germany)
13:40 S8.3 Feeding the clock
J. Johnston (UK)
     
 14:15 15:00    Meet the Expert 6
Willem Burger Auditorium
14:45 MTE6 Difficult adrenal cases
W. Young (USA)
     
 14:15 15:00    Meet the Expert 7
Jurriaanse Auditorium
14:45 MTE7 When to instigate insulin therapy in DM2
J. Skrha (Czech Republic)
     
 14:15 15:00    Meet the Expert 8
Fortis Bank Hall
14:45 MTE8 Management of primary ovarian failure
L. Persani (Italy)
     
 14:15 15:00    Meet the Expert 9
Eduard Flipse Hall
14:45 MTE9 Pleiotropic effects of Vitamin D
M. Pfeifer (Slovenia)
     
 14:15 15:00    Meet the Expert 10
Van Ruckevorsal Hall
14:45 MTE10 Biomarkers of thyroid malignancy
M. Sobrinho-simoes (Portugal)
     
 14:15 15:00    Meet the Expert 11
Van der Vorm Hall
14:45 MTE11 Prolactin and breast tumorogesis: a novel concept of prolactin biology
P. Touraine (France)
     
 15:00 15:20    Coffee Break & Exhibition
Exhibition Hall
     
 15:20 16:50    Symposium 9: New endocrine aspects of diabetes mellitus
Main Auditorium
Chairs: J. Christiansen (Denmark) & A. Scheurink (The Netherlands)
15:20 S9.1 The incretin system: from discovery to drug development
T. Vilsboll (Denmark )
15:50 S9.2 GLP-1 and the cardiovascular system
M. Diamant (The Netherlands)
16:20 S9.3 GLP-1 biology: beyond the pancreas
D. Sandoval (USA)
     
 15:20 16:50    Symposium 10: New developments in the therapy for NETs
Willem Burger Auditorium
Chairs: B. Kos-Kudla (Poland) & G. Kaltsas (Greece)
15:20 S10.1 New developments in the therapy for NETs: risk stratification
M. Pavel (Germany)
15:50 S10.2 Peptide receptor targeted radiotherapy
D. Kwekkeboom (NL )
16:20 S10.3 New drugs including mTOR inhibitors
S. Grozinksky-Glasberg (Israel)
     
 15:20 16:50    Symposium 11: Genetics of male infertility
Fortis Bank Hall
Chairs: M. Maggi (Italy) & P. Touraine (France)
15:20 S11.1 Update on genetics in male infertility
A. Ferlin (Italy )
15:50 S11.2 Clinical aspects of Klinefelter syndrome in childhood, adolescence and adulthood
A. Juul (Denmark)
16:20 S11.3 Genomics of azoospermia
F. Tuttelmann (Germany )
     
 15:20 16:05    Meet the Expert 23
Van Ruckevorsal Hall
15:20 MTE23 Transgenic animals in endocrinology
M. Poutanen (Finland)
     
 16:05 16:50    Meet the Expert 24
Van der Vorm Hall
16:05 MTE24 Stem Cell Biology
C. Alvarez (Spain)
     
 16:55 17:40    Plenary Lecture 2
Main Auditorium
Chair: T. Visser
16:55 PL2 Making sense with thyroid hormone
D. Forrest (USA)
     
 17:40 18:30    Poster Reception
Poster Halls
     
 18:30 20:00    Satellite Symposium: Somatostatin analogues development: what do we learn from recent studies?
Sponsored by Ipsen
Willem Burger Auditorium
Chairs: S. Lambers (The Netherlands) & S. Webb (Spain)
18:30 Approaches to acromegaly treatment resistance
S. Melmed
18:50 A critical analysis of co-administration pegvisomant/somatostatin analogues
D. Ferone (Italy)
19:10 Treatment of polycystic liver disease
F. Nevens (Belgium)
19:30 Mode of administration: clinical importance of injection device and nurse preference
P. Kamenicky (France)
     
 18:30 20:00    Satellite Symposium: Uncovering the intricacies of water and electrolyte balance in Hyponatraemia due to SIADH
Spnsored by Otsuka
Jurriaanse Auditorium
Chair: C. Thompson
18:30 Welcome & Introduction
C. Thompson
18:35 Uncovering the intricacies of water and electrolyte balance in hyponatraemia due to SIADH
R. Schrier
19:00 Considerations for the appropriate diagnosis and treatment of hyponatraemia due to SIADH
C. Thompson
19:25 Clinical application of treatment considerations: Case example
A. Peri
19:50 Questions and answers
     
 18:30 20:00    Satellite Symposium: 5 years and counting: insights from ACROSTUDY
Sponsored by Pfizer
Main Auditorium
Chair: E. Ghigo (Italy)
18:30 Introduction and study overview
E. Ghigo (Italy)
18:55 Pegvisomant: long-term clinical outcomes
C. Strasburger (Germany)
19:15 Safety observations from the treatment of acromegaly
AJ van der Lely (The Netherlands)
19:35 Tumour volume change: central anaylsis of MRIs in ACROSTUDY
M. Buchfelder (Germany)
19:40 Summary & Q&A
     
 20:30 00:00    ECE 25th Anniversary Evening (Ticket Only)
Transport will be provided
Cruise Terminal, Rotterdam
     
2 May 2011
 07:00 20:00    Registration
     
 08:00 08:45    Plenary Lecture 3
Main Auditorium
Chair: S. Lamberts
08:00 PL3 Targets for the management of diabetes in 2011
J. Christiansen (Denmark )
     
 08:50 10:20    Symposium 12: Novel insights into phosphate metabolism
Main Auditorium
Chairs: N. Hamdy (The Netherlands) & J. Bollerslev (Norway)
08:50 S12.1 The maintenance of phosphate homeostasis by FGF23
O. Ljunggren (Sweden)
09:20 S12.2 Genetic disorders of phosphate metabolism
G. Hampson (UK)
09:50 S12.3 FGF23: marker or predictor of progression in chronic kidney disease
D. Prie (France)
     
 08:50 10:20    Oral Communication 1
Jurriaanse Auditorium
Chairs: D. Carvalho (Portugal) & M. Niedziela (Poland)
08:50 OC1.1 Maternal first trimester thyroid hormone levels within the normal range affect birth weight: results from a large population-based cohort study
Presenter: M Medici
09:05 OC1.2 Smoking habits and early pregnancy thyroid hormone and antibody levels
Presenter: T Männistö
09:20 OC1.3 Maternal thyroid dysfunction during pregnancy and thyroid function of the offspring at the age of 16 years
Presenter: Fanni Päkkilä
09:35 OC1.4 Results of 1,Ortho-1,para’-Dichloro-Diphenyl-Dichloroethane (O,p’DDD) treatment in 76 patients with Cushing’s Disease
Presenter: C. Baudry
09:50 OC1.5 Adrenal crisis and general morbidity in chronic adrenal insufficiency prospectively assessed in 472 patients
Presenter: Stefanie Hahner
10:05 OC1.6 Increased risk of infections in patients with Addison’s disease
Presenter: l.c.c.j. Smans
     
 08:50 10:20    Oral Communication 2
Eduard Flipse Hall
Chairs: P. Burman (Sweden) & AJ van der Lely (The Netherlands)
08:50 OC2.1 Etoposide, doxorubicin, cisplatin, and mitotane versus streptozotocin and mitotane in adrenocortical carcinoma – preliminary results from the first international phase III trial - the FIRM-ACT study
Presenter: Martin Fassnacht
09:05 OC2.2 Gonadotropin responses to kisspeptin are modulated by changes in aminoacidergic and neuropeptidergic neurotransmission: Studies in peripubertal male rats
Presenter: R. Pineda
09:20 OC2.3 Distribution of serotonin transporters in the human hypothalamus
Presenter: A.J. Borgers
09:35 OC2.4 Genetic and molecular cytogenetic investigations in Turner Syndrome patients with spontaneous pubertal development
Presenter: R Rossetti
09:50 OC2.5 Risk of cardiac valve regurgitation with dopamine agonist use in Parkinson’s disease and hyperprolactinemia
Presenter: G Trifirò
10:05 OC2.6 The spectrum and causes of gonadal dysfunction in adolescents and adults with Prader-Willi Syndrome (PWS)
Presenter: Talia Eldar-Geva
     
 10:20 10:40    Coffee Break & Exhibition
Exhibition Hall
     
 10:40 11:40    Debate 2: This house believes the future management of all pituitary adenomas will be medical
For: S. Lamberts. Against: R. Fahlbusch
Main Auditorium
Chair: P. Trainer (UK)
     
 10:40 11:25    Meet the Expert 12
Willem Burger Auditorium
10:40 MTE12 Treatment of strategies for obesity
D. Micic (Serbia)
     
 10:40 11:25    Meet the Expert 13
Jurriaanse Auditorium
10:40 MTE13 SIADH
C. Thompson (Ireland)
     
 10:40 11:25    Meet the Expert 14
Fortis Bank Hall
10:40 MTE14 Graves’ Ophthalmopathy
W. Wiersinga (The Netherlands)
     
 10:40 11:25    Meet the Expert 15
Van der Vorm Hall
10:40 MTE15 Cushing's
S. Webb (Spain)
     
 10:40 11:25    Meet the Expert 16
Van Ruckevorsal Hall
10:40 MTE16 Endocrine care in HIV-infected patients
V. Rochira (Italy)
     
 11:45 13:15    Symposium 13: Endocrine response to critical illness
Willem Burger Auditorium
Chairs: E. Fliers (The Netherlands) & I. Lazurova (Slovakia)
11:45 S13.1 The HPA axis in critical illness
D. Annane (France )
12:15 S13.2 Thyroid hormone metabolism in inflammation and sepsis
A. Boelen (NL )
12:45 S13.3 Novel insights in endocrine and metabolic changes during critical illness
G. van den Berge (Belgium )
     
 11:45 13:15    Symposium 14: Female contraception update
Jurriaanse Auditorium
Chairs: S. Christin-Maitre (France) & A. Milewicz (Poland)
11:45 S14.1 Compliance and the risk of pregnancy
A. Glasier (UK)
12:15 S14.2 New pills
R. Sitruk-Ware (USA)
12:45 S14.3 Emergency Contraception
K. Gemzell-Danielsson (Sweden )
     
 11:45 13:15    Symposium 15: Emerging therapies in type 2 diabetes
Main Auditorium
Chairs: B. Wolffenbuttel (The Netherlands) & I. Konrade (Latvia)
11:45 S15.1 Emerging therapies in type 2 diabetes: bariatric surgery
H. Cardoso (Portugal )
12:15 S15.2 11 beta Hydrooxysteroid dehaydrogenase inhibitors for treatment of metabolic syndrome
P. Stewart (UK )
12:45 S15.3 Future therapies - what is in the pipeline?
S. S. Torekov (Denmark)
     
 11:45 12:30    Meet the Expert 24 (REPEATED)
Van der Vorm Hall
11:45 MTE24 Stem Cell Biology
C. Alvarez (Spain)
     
 12:30 13:15    Meet the Expert 23 (REPEATED)
Van Ruckevorsal Hall
12:30 MTE23 Transgenic animals in endocrinology
M. Poutanen (Finland)
     
 13:15 14:00    Lunch & Exhibition
ESE President meets new members of ESE (invitation only)
Exhibition Hall
     
 14:00 14:45    Meet the Expert 6 (REPEATED)
Willem Burger Auditorium
14:00 MTE6 Difficult adrenal cases
W. Young (USA)
     
 14:00 14:45    Meet the Expert 18
Jurriaanse Auditorium
14:00 MTE18 Weird thyroid function tests
M. Gurnell (UK)
     
 14:00 14:45    Meet the Expert 19
Fortis Bank Hall
14:00 MTE19 Management of primary hyperparathyroidism
J. Bollerslev (Norway)
     
 14:00 14:45    Meet the Expert 20
Eduard Flipse Hall
14:00 MTE20 Glucocorticoid replacement therapy
K. Lovas (Norway)
     
 14:00 14:45    Meet the Expert 21
Van Ruckevorsal Hall
14:00 MTE21 To whom to offer genetic analysis in patients with pituitary adenoma
A. Beckers (Belgium)
     
 14:00 14:45    Meet the Expert 22
Van der Vorm Hall
14:00 MTE22 Diabetes and the genome. Any use for our patients?
A-M Wagner (Spain)
     
 14:50 16:20    Symposium 16: TSH Receptor and thyroid disorders
Willem Burger Auditorium
Chairs: J. Koehrle (Germany) & L. Persani (Italy)
14:50 S16.1 TSH receptor antibodies
J. Sanders (UK )
15:20 S16.2 Activating and inactivating TSH receptor mutations
R. Paschke (Germany )
15:50 S16.3 Small-molecule TSH receptor ligands
S. Neumann (USA )
     
 14:50 16:20    Symposium 17: Pituitary Update
Jurriaanse Auditorium
Chairs: J. Marek (Czech Republic) & R. Pivonello (Italy)
14:50 S17.1 Radiosurgery and radiotherapy of pituitary addenomas
F. Castinetti (France )
15:20 S17.2 Update on pituitary surgery 2011
J. Honegger (Germany )
15:50 S17.3 Pituitary late effects of radiotherapy for brain tumours
M. Bolanowski (Poland )
     
 14:50 16:20    Symposium 18: Management of endocrine disease in pregnancy
Main Auditorium
Chairs: P. Caron (France) & T. Rajasalu (Estonia)
14:50 S18.1 Type-1 diabetes and pregnancy
P. Damm (Denmark )
15:20 S18.2 Type-2 diabetes in pregnancy
E. Anastasiou (Greece)
15:50 S18.3 Thyroid autoimmunity in pregnancy
K. Poppe (Belgium )
     
 16:20 16:40    Coffee Break & Exhibition
Exhibition Hall
     
 16:40 16:55    JME Prize Presentation
Main Auditorium
     
 16:55 17:40    Plenary Lecture 4
Main Auditorium
Chair: A. Themmen
16:55 PL4 Gonadotrophin signaling in health and disease
I. Huhtaniemi (Finland )
     
 17:40 18:30    Poster Reception
Poster Halls
     
 18:30 20:00    Satellite Symposium: Meet the Experts - Practical considerations in hyponatraemia: An interactive case study session
Sponsored by Otsuka
Jurriaanse Auditorium
Chair: G. Johannsson
18:30 Welcome & Introduction
G. Johannsson
18:45 Case Study 1
A. Peri
19:10 Case Study 2
V. Burst
19:35 Questions & Answers
     
 18:30 20:00    Satellite Symposium: Cushing's Disease - the case for long-term follow up
Sponsored by Novartis
Main Auditorium
Chair: S. Lamberts (The Netherlands)
18:30 Welcome & Introduction
S. Lamberts (The Netherlands)
18:40 Cushing's Disease case by case
A. Tabarin (France)
19:00 Strategies for improving outcomes for the patient with Cushings disease
B. Biller (USA)
19:20 Maintaining glycemic control during medical treatment for Cushing's disease
R. Henry (USA)
19:40 Summary, panel discussion and concluding remarks
     
 18:30 20:00    Satellite Symposium: New insights in adrenal cortical carcinoma
Sponsored by HRA Pharma
Willem Burger Auditorium
Chairs: G. Hammer & X. Bertagna
18:30 Emerging prognosis markers for survival and progress in ACC classification
E. Baudin
19:00 Revisiting mitotane therapy
M. Terzolo
19:30 New data on the treatment of advanced ACC
HR Haak
     
 20:00 21:30    Endocrine Nurses' Networking Meeting
     
3 May 2011
 07:00 20:00    Registration
     
 08:00  08:45    Plenary Lecture 5
Main Auditorium
Chair: P. Trainer
08:00 PL5 Endocrine hypertension
W. Young (USA )
     
 08:50 10:20    Symposium 19: Management of endocrine disease in adolescence
Main Auditorium
Chairs: E. van den Akker (The Netherlands) & J. Cap (Czech Republic)
08:50 S19.1 Management of congenital adrenal hyperplasia (CAH) in adolescence
H. Claahsen-van der Grinten (NL)
09:20 S19.2 The challenges of managing childhood cancer survivors during adolescence
H. Gleeson (UK )
09:50 S19.3 Management of type-1 diabetes in adolescence
Z. Sumnik (Czech Republic )
     
 08:50 10:20    Oral Communication 3
Jurriaanse Auditorium
Chairs: G. Williams (UK) & M. Simoni (Italy)
08:50 OC3.1 Mild Hyponatremia as a Risk Factor for Fractures: The Rotterdam Study
Presenter: C Zillikens
09:05 OC3.2 Changes in serum magnesium levels during cinacalcet therapy for primary hyperparathyroidism
Presenter: V. Daraki
09:20 OC3.3 Evolution of Neurobehavioral and Cognitive Symptoms in Patients with Primary Hyperparathyroidism Belonging to the Swiss Primary Hyperparathyroidism Cohort
Presenter: A Trombetti
09:35 OC3.4 Low doses of bisphenol A promote human seminoma cell proliferation in vitro by activating PKA and PKG via the non classical membrane G protein-coupled estrogen receptor (GPER)
Presenter: P. Fénichel
09:50 OC3.5 IGF-I PROMOTES SURVIVAL OF MAST CELLS AND REGULATES THEIR NUMBER IN THE DEVELOPING MAMMARY GLAND
Presenter: P. Ameri
10:05 OC3.6 Materno-Fetal Cardiovascular Complications in Turner Syndrome after Oocyte Donation: a French multicenter retrospective study
Presenter: N. Chevalier
     
 08:50 10:20    Oral Communication 4
Eduard Flipse Hall
Chairs: V. Pirags (latvia) & R. Elisei (Italy)
08:50 OC4.1 Obestatin improves in vitro generation of novel insulin and glucagon secreting islet-like cell clusters from islet-derived non differentiated cells.
Presenter: A Baragli
09:05 OC4.2 Hepatic insulin resistance in rats on free-choice high-fat diets
Presenter: C Diepenbroek
09:20 OC4.3 Association of genetic polymorphisms in the organic cation transporters OCT1, OCT2 and multidrug and toxin extrusion 1 transporter protein with the metformin intolerance and weight lowering in patients of type 2 diabetes
Presenter: J Klovins
09:35 OC4.4 HLA-G Polymorphism and Papillary Thyroid Cancer Histological Aggressiveness
Presenter: A Dardano
09:50 OC4.5 Comparison of four strategies of radioiodine ablation in patients with thyroid cancer with low-risk of recurrence: the randomized, prospective ESTIMABL study
Presenter: L Leenhardt
10:05 OC4.6 No causal relationship between Yersinia enterocolitica infection and autoimmune thyroid disease: evidence from a prospective study
Presenter: G. Effraimidis
     
 08:50 10:20    Oral Communication 5
Fortis Bank Hall
Chairs: R. Nogueiras (Spain) & W. Arlt (UK)
08:50 OC5.1 HDL receptor SR-BI dysfunction is associated with a diminished adrenal glucocorticoid output in mice and man
Presenter: M Hoekstra
09:05 OC5.2 Site specific overexpression of Urocortin 2 results in modulation of steroidogenesis in vivo
Presenter: A Spyroglou
09:20 OC5.3 Identification of melanocortin 2 receptor structures responsible for specific membrane expression and ACTH binding specificity
Presenter: J Klovins
09:35 OC5.4 Adrenal melanocortin 2 receptor associated protein (MRAP) expression is regulated by ACTH and angiotensin II, whereas MRAP2 levels are associated with ACTH responsiveness
Presenter: J Hofland
09:50 OC5.5 The effect of MCT8 on the biological activity of T3
Presenter: A.A.A. van Mullem
10:05 OC5.6 A novel non-radioactive assay detects PTU-sensitive enzymatic deiodination of natural and synthetic iodinated compounds
Presenter: K Renko
     
 10:20 10:45    Coffee Break & Exhibition
Exhibition Hall
     
 10:45 12:15    Symposium 20: Thyroid function: it is in your genes
Main Auditorium
Chairs: H. Krude (Germany) & R. Paschke (Germany)
10:45 S20.1 Genetics versus Environment - what determines thyroid function?
P. Hansen (Denmark )
11:15 S20.2 Polymorphic variation in thyroid pathways genese
R. Peeters (NL)
11:45 S20.3 Genetic of autoimmune thyroid disease
M. Simmonds (UK )
     
 10:45 12:15    Symposium 21: Vitamin D, pregnancy and development
Willem Burger Auditorium
Chairs: Z. Hochberg (Israel) & TBC
10:45 S21.1 Evolutionary Perspective in vitamin D and its receptor VDR
Z. Hochberg (Israel )
11:15 S21.2 Vitamin D deficiency and supplementation in pregnancy
P. Lips (NL )
11:45 S21.3 Maternal vitamin D intake and risk of type-1 diabtes in offspring
S. Virtanen (Finland )
     
 10:45 12:15    Symposium 22: Non traditional effects of pituitary hormones
Jurriaanse Auditorium
Chairs: V. Popovic-Brkic (Serbia) & F. Kelestimur (Turkey)
10:45 S22.1 Non thyroidal effects of TSH
G. Williams (UK )
11:15 S22.2 Vasopressin and social odour processing in the olfactory system
M. Ludwig (UK )
11:45 S22.3 Prolactin, stem cells and prostate cancer
V. Goffin (France )
     
 12:15 13:00    Lunch & Exhibition
Exhibition Hall
     
 13:00 13:45    Meet the Expert 1 (REPEATED)
Willem Burger Auditorium
13:00 MTE1 Pros and cons of bariatric surgery
J. Salvador (Spain)
     
 13:00 13:45    Meet the Expert 2(REPEATED)
Jurriaanse Auditorium
13:00 MTE2 Primary hyperaldosteronism
M.Stowasser (Australia)
     
 13:00 13:45    Meet the Expert 3: (REPEATED)
Fortis Bank Hall
13:00 MTE3 Difficult recurrences and metastasis of thyroid cancer
L. Leenhardt (France)
     
 13:00 13:45    Meet the Expert 4 (REPEATED)
Van Ruckevorsal Hall
13:00 MTE4 Mass spectrometry in the measurement of hormones
U. Pagotto (Italy)
     
 13:00 13:45    Meet the Expert 5 (REPEATED)
Van der Vorm Hall
13:00 MTE5 How to write a manuscript - Meet the Editor
C. Strasburger (Germany)
     
 13:50 14:35    Meet the Expert 17
Willem Burger Auditorium
13:50 MTE17 Management of Phaeochromocytomas and paragangliomas
P-F. Plouin (France)
     
 13:50 14:35    Meet the Expert 7 (REPEATED)
Jurriaanse Auditorium
13:50 MTE7 When to instigate insulin therapy in DM2
J. Skrha (Czech Republic)
     
 13:50 14:35    Meet the Expert 8 (REPEATED)
Fortis Bank Hall
13:50 MTE8 Management of primary ovarian failure
L. Persani (Italy)
     
 13:50 14:35    Meet the Expert 9 (REPEATED)
Eduard Flipse Hall
13:50 MTE9 Pleiotropic effects of Vitamin D
M. Pfeifer (Slovenia)
     
 13:50 14:35    Meet the Expert 10 (REPEATED)
Van Ruckevorsal Hall
13:50 MTE10 Biomarkers of thyroid malignancy
M. Sobrinho-Simoes (Portugal)
     
 13:50 14:35    Meet the Expert 11 (REPEATED)
Van der Vorm Hall
13:50 MTE11 Prolactin and breast tumorogesis: a novel concept of prolactin biology
P. Touraine (France)
     
 14:35 15:00    Coffee Break & Exhibition
Exhibition Hall
     
 15:00 16:30    Symposium 23: Optimising thyroid hormone replacement
Main Auditorium
Chairs: L. Fugazzola (Italy) & P. Laurberg (Denmark)
15:00 S23.1 Is there a place for combined T4 and T3 replacement therapy?
A. Weetman (UK )
15:30 S23.2 Thyroid dysfunction in the elderly
K. Boelaert (UK )
16:00 S23.3 Failure of thyroxine replacement to suppress TSH - what to do now?
J. Orgiazzi (France )
     
 15:00 16:30    Symposium 24: Management of phaechromocytoma
Willem Burger Auditorium
Chairs: M. Mannelli (Italy) & TBC
15:00 S24.1 Biochemical screening for phaechromocytoma using plasma free metanephrines: utility beyond diagnosis
G. Eisenhofer (Germany )
15:30 S24.2 Imaging of phaechromocytoma and paragangliomas
H. Timmers (NL )
16:00 S24.3 Surgical Therapy
B. Niederle (Austria )
     
 15:00 16:30    Symposium 25: GNAS locus: imprinting, animal models and human diseases
Jurriaanse Auditorium
Chairs: A. Tsatsoulis (Greece) & A. Barlier (France)
15:00 S25.1 Genomic imprinting of the GNAS locus
G. Kelsey (UK )
15:30 S25.2 Epigenetic defects at the GNAS locus and human diseases
G. Mantovani (Italy)
16:00 S25.3 Xlas, in vitro functions and possible physiological and pathogenetic role
A. Linglart (France )
     
 16:35 16:50    ESE Young Investigator Awards & Poster Prizes
Generously supported by Novartis
Main Auditorium
     
 16:55 17:40    Plenary Lecture 6
Main Auditorium
Chair: P. Bouchard
16:55 PL6 Neurosteroids as Regenerative Agents in Brain: Therapeutic Implications for Cognition and Neurodegenerative Disease
R. Brinton (USA )
     
 17:40 18:30    Poster Reception
Poster Halls
     
 18:30 20:00    Annual General Meeting of the European Society of Endocrinology (ESE)
Willem Burger Auditorium
     
 20:30     President's Dinner
Invitation Only
     
4 May 2011
 07:45 14:00    Registration
     
 08:00 09:30    Symposium 26: The role of plasma binding proteins in tissue hormone delivery
Fortis Bank Hall
Chairs: M. Pugeat (France) & P. Rodien (France)
08:00 S26.1 Sex Hormone-binding Globulin: Beyond Plasma Transport
G. Hammond (Canada)
08:30 S26.2 The role of IGFBPs in the tissue-specific actions of IGFs
J.M.P. Holly (UK)
09:00 S26.3 The role of TTR in tissue delivery of thyroid hormone
M. J. Saraiva (Portugal )
     
 08:00 09:30    Symposium 27: Breaking news in adrenal malignancy
Jurriaanse Auditorium
Chairs: B. Allolio (Denmark) & S. Tsagarakis (Greece)
08:00 S27.1 European Network for the Study of Adrenal Tumours: Adrenal Cancer Consortium (ENS@T-CANCER)
F. Beuschlein (Germany)
08:30 S27.2 Transcriptome analysis and microRNAs in adrenal tumours
P. Igaz (Hungary)
09:00 S27.3 Management of adrenocorticol carcinoma - what have we learnt from recent trials?
M. Fassnacht (Germany)
     
 08:00 09:30    Symposium 28: Polycystic ovary syndrome - Classification, genetics and therapy
Main Auditorium
Chairs: R. Pasquali (Italy) & E. Diamanti-Kandarakis (Greece)
08:00 S28.1 Phenotypes and environmental factors
E. Diamanti-Kandarakis (Greece)
08:30 S28.2 Genetics
S. Franks (UK)
09:00 S28.3 Treatment of infertility and prediction of success
B. Fauser (The Netherlands)
     
 08:00 09:30    From Fat to Sex - Young Endocrine Research Across Europe
Young Active Research (YAR) Symposium
Eduard Flipse Hall
Chairs: F. Moeller & S. Neggers (Germany)
08:05 YAR1 Does puberty begin with a Kiss?
A. Bentsen (Denmark)
08:30 YAR2 Development of a mouse model with PCOS
L. van Houten (The Netherlands)
08:45 YAR3 Somatic sex reprogramming by FOXL2 deletion
H. Uhlenhaut (Germany)
09:10 YAR4 Small animal PET/CT imaging reveals altered in vivo insulin function in BAT of obese mice
C. Quarta (Italy)
     
 09:35 10:20    Plenary Lecture 7
Main Auditorium
Chair: M. Simoni (Italy)
09:35 PL7 Androgen use and misuse: A 2011 view
D. Handelsman (Australia)
     
 10:20 10:45    Coffee Break & Exhibition
Exhibition Hall
     
 10:45 11:30    Meet the Expert 12 (REPEATED)
Willem Burger Auditorium
10:45 MTE12 Treatment of strategies for obesity
D. Micic (Serbia)
     
 10:45 11:30    Meet the Expert 13 (REPEATED)
Jurriaanse Auditorium
10:45 MTE13 SIADH
C. Thompson (Ireland)
     
 10:45 11:30    Meet the Expert 14 (REPEATED)
Fortis Bank Hall
10:45 MTE14 Graves’ Ophthalmopathy
W. Wiersinga (The Netherlands)
     
 10:45 11:30    Meet the Expert 15 (REPEATED)
Eduard Flipse Hall
10:45 MTE15 Cushing's
S. Webb (Spain)
     
 10:45 11:30    Meet the Expert 16 (REPEATED)
Van der Vorm Hall
10:45 MTE16 Endocrine care in HIV-infected patients
V. Rochira (Italy)
     
 11:35 12:20    Meet the Expert 17(REPEATED)
Willem Burger Auditorium
10:45 MTE17 Management of Phaeochromocytomas and paragangliomas
P-F. Plouin (France)
     
 11:35 12:20    Meet the Expert 18 (REPEATED)
Jurriaanse Auditorium
11:35 MTE18 Weird thyroid function tests
M. Gurnell (UK)
     
 11:35 12:20    Meet the Expert 19 (REPEATED)
Fortis Bank Hall
11:35 MTE19 Management of primary hyperparathyroidism
J. Bollerslev (Norway)
     
 11:35 12:20    Meet the Expert 20 (REPEATED)
Eduard Flipse Hall
11:35 MTE20 Glucocorticoid replacement therapy
K. Lovas (Norway)
     
 11:35 12:20    Meet the Expert 21 (REPEATED)
Van Ruckevorsal Hall
11:35 MTE21 To whom to offer genetic analysis in patients with pituitary adenoma
A. Beckers (Belgium)
     
 11:35 12:20    Meet the Expert 22 (REPEATED)
Van der Vorm Hall
11:35 MTE22 Diabetes and the genome. Any use for our patients?
A-M Wagner (Spain)
     
 12:25 13:10    Plenary Lecture 8
Main Auditorium
Chair: P. Lips
12:25 PL8 Genetics of bone disease
S. Ralston (UK)
     
 13:10 13:25    Farewell & Invitation to Florence
Main Auditorium